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LIMK-1 Polyclonal Antibody, 20ul[BT-AP05018] Polyclonal Antibodies KLF13 belongs to a family

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LIMK-1 Polyclonal Antibody, 20ul[BT-AP05018] Polyclonal Antibodies KLF13 belongs to a familyThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

Store: gaabil.dk · Domain: gaabil.dk

Description

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif)

whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells

A related pseudogene has been found on chromosome 6

transcription activation and apoptosis

12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells

LIMK-1 Polyclonal Antibody, 20ul[BT-AP05018] Polyclonal Antibodies KLF13 belongs to a familyThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

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