MICU1 Monoclonal Antibody(Mix), 20ul Site-directed Mutagenesis and in HeLa cells

and in HeLa cells

an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation

which encode two distinct isoforms

which are stem-loop structures found in the 5' UTR of ferritin mRNA

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MICU1 Monoclonal Antibody(Mix), 20ul Site-directed Mutagenesis and in HeLa cellsThis gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.