ZNRF1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in the coding region

Mutations in the coding region of this gene are associated with Bruck syndrome

a member of the potassium channel

This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness

Male mice which lack TSSK6 encoding a highly similar protein are sterile and have morphologically abnormal sperm

Because of its many functions

ZNRF1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in the coding regionThis gene encodes an E3 ubiquitin protein ligase that plays a role in neural cell differentiation. Overexpression of this gene causes neurite like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome lysosome compartment, indicating that it may be involved in ubiquitin mediated protein modification, and in synaptic vessicle membranes in neurons.