UVRAG Polyclonal Antibody, 50ul Organelle Studies Deficiency of this enzyme is

Deficiency of this enzyme is generally asymptomatic

Upregulation of this gene has been associated with hepatocellular carcinomas

The encoded protein may play a role in endocytic trafficking

tissue specificity:Expressed predominantly in lung

This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH

UVRAG Polyclonal Antibody, 50ul Organelle Studies Deficiency of this enzyme isThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.