MSH3 Polyclonal Antibody, 100ul Biomatrix This gene is predicted to

This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor

enabling proper chromosome segregation

and its upregulation during differentiation

Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway

but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein

MSH3 Polyclonal Antibody, 100ul Biomatrix This gene is predicted toDNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3 7 repeats have been reported.