KLF8 Polyclonal Antibody, 50ul Pipette Filler The subunit encoded by this

The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide

The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing

heterodimerize with the related platelet-derived growth factor subunit A

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities

a group of integral membrane proteins characterized by the presence of cadherin-type repeats

KLF8 Polyclonal Antibody, 50ul Pipette Filler The subunit encoded by thisKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.