PEA-15(Phospho Ser116) Polyclonal Antibody, 100ul Cell Labeling & Imaging cofactor:Binds 2 zinc ions per

cofactor:Binds 2 zinc ions per subunit

An important paralog of this gene is TXNDC12

The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK

The protein is cytosolic at resting calcium levels

Adapted to 13×75mm

PEA-15(Phospho Ser116) Polyclonal Antibody, 100ul Cell Labeling & Imaging cofactor:Binds 2 zinc ions perThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.