NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation a member of the thyroid-steroid

a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators

and stress-induced genes

implicated in a variety of cellular processes

although its function has not been well established

The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation a member of the thyroid-steroidProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.