NFKappaB-p105/p50 Polyclonal Antibody, 100ul[BT-AP05981] Liquid Handling ＆Storage This component is a heteromeric

This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

which are composed of alpha- and beta-tubulin heterodimers and microtubule-associated proteins in the cytoskeleton

May be involved in reorganization of the cortical cytoskeleton

Was originally (PubMed:2480877) thought to be myoblast cell surface antigen 24

and overexpression of this gene has been implicated in tumor metastasis

NFKappaB-p105/p50 Polyclonal Antibody, 100ul[BT-AP05981] Liquid Handling ＆Storage This component is a heteromericNFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and