Paxillin Polyclonal Antibody, 50ul[BT-AP06956] PCR Series similar to Vps4 protein in

similar to Vps4 protein in yeast

Gene Ontology (GO) annotations related to this gene include calmodulin binding and Ras GTPase binding

An important paralog of this gene is IGHG4

Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma

Pseudogenes related to this gene are located on chromosomes 1

Paxillin Polyclonal Antibody, 50ul[BT-AP06956] PCR Series similar to Vps4 protein inPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.