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CD55 Polyclonal Antibody, 100ul[BT-AP01917] Gene Synthesis This gene maps in a

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CD55 Polyclonal Antibody, 100ul[BT-AP01917] Gene Synthesis This gene maps in aCOL1A2 encodes the pro alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I IV, Ehlers Danlos syndrome type VIIB, recessive Ehlers Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan

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Description

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

FOXD4L1 is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains

compared to isoform a

The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products

CD55 Polyclonal Antibody, 100ul[BT-AP01917] Gene Synthesis This gene maps in aCOL1A2 encodes the pro alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I IV, Ehlers Danlos syndrome type VIIB, recessive Ehlers Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan

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