c-Src(Phospho Tyr419) Polyclonal Antibody, 100ul[BT-AP06923] Bio-Reaction Tube IKBKE has also been identified

IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors

proliferation of endothelial cells

EPH and EPH-related receptors have been implicated in mediating developmental events| particularly in the nervous system

The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression

c-Src(Phospho Tyr419) Polyclonal Antibody, 100ul[BT-AP06923] Bio-Reaction Tube IKBKE has also been identifiedThis gene is highly similar to the v src gene of Rous sarcoma virus. This proto oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine protein kinase whose activity can be inhibited by phosphorylation by c SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for