TPH1 Polyclonal Antibody, 20ul[BT-AP09151] Virus Packaging Other xenobiotic substrates for this

Other xenobiotic substrates for this enzyme include caffeine

The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH

inhibits the membrane-damaging effect of the terminal cytolytic complement pathway

and also with susceptibility to colorectal and lung cancers

which contains a trinucleotide repeat (CAG) length polymorphism

TPH1 Polyclonal Antibody, 20ul[BT-AP09151] Virus Packaging Other xenobiotic substrates for thisTPH1 encodes a member of the aromatic amino acid hydroxylase family. The tryptophan 5 hydroxylase 1 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.