SIR4 Polyclonal Antibody, 20ul sgRNA Oligos Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for CNTROB

2003 [PubMed 12881038])

and is caused by mutations in the WAS gene

resulting in members with and without DNA-binding properties

The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction

SIR4 Polyclonal Antibody, 20ul sgRNA Oligos Alternatively spliced transcript variants encodingThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular