IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants encoding the same protein

The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6

limiting DNA accessibility to the cellular machineries which require DNA as a template

They are also characterized by a catalytic triad composed of a histidine

this gene has been found to be hypermethylated in multiple cancer types

IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis Alternative splicing results in multipleIRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor associated