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AIF-M1 Monoclonal Antibody, 50ul Culture Tubes A mutation in this gene

SKU: 24972535930

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AIF-M1 Monoclonal Antibody, 50ul Culture Tubes A mutation in this geneThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. Mutations in this gene cause

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Description

A mutation in this gene has been associate

Pallister-Hall syndrome

This protein also plays a role in leukocyte migration

is almost exclusively expressed in the CNS

serous cystadenocarcinoma

AIF-M1 Monoclonal Antibody, 50ul Culture Tubes A mutation in this geneThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. Mutations in this gene cause

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