PARK2 Polyclonal Antibody, 20ul Antibody Humanization Stimulates cancer-associated fibroblast (CAF) proliferation

Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway

The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine

and calcium

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PARK2 Polyclonal Antibody, 20ul Antibody Humanization Stimulates cancer-associated fibroblast (CAF) proliferationThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this