Smad3 Polyclonal Antibody, 100ul[BT-AP08391] Cell Labeling & Imaging |tissue specificity:Expressed in thymus| T-cells|

|tissue specificity:Expressed in thymus| T-cells| NK cells| mast cells and| at lower levels| in spleen

The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi

It catalyzes its autophosphorylation on serine/threonine and tyrosine residues

although this effect could be indirect

which is thought to contribute to the inflammatory response and host defense

Smad3 Polyclonal Antibody, 100ul[BT-AP08391] Cell Labeling & Imaging |tissue specificity:Expressed in thymus| T-cells|The protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of