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IKK gamma Polyclonal Antibody, 20ul[BT-AP10268] Roller Bottles MIM 603034)

SKU: 22454729730

4.6
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IKK gamma Polyclonal Antibody, 20ul[BT-AP10268] Roller Bottles MIM 603034)This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Store: gaabil.dk · Domain: gaabil.dk

Description

MIM 603034)

The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein

cell division

can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor

Homotetramers consisting of the intact protein| or type C subunit| exhibit high affinity for heparin and are anchored to the ECM

IKK gamma Polyclonal Antibody, 20ul[BT-AP10268] Roller Bottles MIM 603034)This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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