FoxO4 Polyclonal Antibody, 20ul[BT-AP03337] Supplements Loss of function mutations result

Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

including pseudopodia formation

This gene has also been linked to a susceptibility to type I diabetes in women

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FoxO4 Polyclonal Antibody, 20ul[BT-AP03337] Supplements Loss of function mutations resultFOXO4 encodes a member of the O class of winged helix forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants