SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter Upon phosphorylation

Upon phosphorylation

Mutations in this gene are a cause of spastic ataxia 2| autosomal recessive

This gene is co-transcribed with the U69 small nucleolar RNA gene

which may serve as a membrane anchor

Alternative splicing results in multiple tr

SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter Upon phosphorylationSIM1 and SIM2 genes are Drosophila single minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull