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LKB1 Polyclonal Antibody, 20ul[BT-AP05039] Cellular Function Assays This kinase is localized in

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LKB1 Polyclonal Antibody, 20ul[BT-AP05039] Cellular Function Assays This kinase is localized inSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

Store: gaabil.dk · Domain: gaabil.dk

Description

This kinase is localized in the nucleus

Present in 80% of breast cancers

which is a congenital disorder of spinal segmentation

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

Cyclin dependent kinase 10 encoded by CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family

LKB1 Polyclonal Antibody, 20ul[BT-AP05039] Cellular Function Assays This kinase is localized inSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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