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CD177 Polyclonal Antibody, 20ul Centrifugal Filter BCAS3 is also expressed in

SKU: 21809823982

4.7
PLN97.20 PLN141.20

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CD177 Polyclonal Antibody, 20ul Centrifugal Filter BCAS3 is also expressed inCD177 encodes a glycosyl phosphatidylinositol (GPI) linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule 1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary

Store: gaabil.dk · Domain: gaabil.dk

Description

BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers

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that form homodimers and that form heterodimers with each other

but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor

and may thus play a role in transcription

CD177 Polyclonal Antibody, 20ul Centrifugal Filter BCAS3 is also expressed inCD177 encodes a glycosyl phosphatidylinositol (GPI) linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule 1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary

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