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TOP1M Polyclonal Antibody, 100ul Filtration It is involved in muscle

SKU: 21604905343

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TOP1M Polyclonal Antibody, 100ul Filtration It is involved in muscleThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events

Multiple alleles of this gene exhibiting variations in the length of the tandem repeats| polymorphic cleavage sites and polymorphic stop codons have been identified

The beta-1

They are also characterized by a catalytic triad composed of a histidine

but our experiment always detected a 60-70kDa protein by western blot

TOP1M Polyclonal Antibody, 100ul Filtration It is involved in muscleThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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