COP1(Phospho Ser387) Polyclonal Antibody, 20ul Dry Bath Cleft palate with ankyloglossia

Cleft palate with ankyloglossia

Two alternatively spliced transcript variants encoding different isoforms have been described for this gene

with strong preference for histone H4

but there is evidence that cells may not be able to engage in both activities at the same time

or they may include only the gene-specific exons

COP1(Phospho Ser387) Polyclonal Antibody, 20ul Dry Bath Cleft palate with ankyloglossiaThe RING finger domain, in addition to its role in ubiquitination, functions as a structural scaffold to bring two clusters of positive charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS).,E3 ubiquitin protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester