Phospho-Akt (S473) Polyclonal Antibody, 50ul[BT-PHS00864] Lentiviral Packaging Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different isoforms have been described for this gene

The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine

SIX homeobox 5 encoded by SIX5 is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis

a major risk factor for coronary artery disease

The TRAF family member associated NFKB activator encoded by TANK is found in the cytoplasm and can bind to TRAF1

Phospho-Akt (S473) Polyclonal Antibody, 50ul[BT-PHS00864] Lentiviral Packaging Three alternatively spliced transcript variantsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a