Raf-1 Polyclonal Antibody, 20ul[BT-AP13535] Immunoassays Peroxisomal biogenesis factor 11 beta

Peroxisomal biogenesis factor 11 beta encoded by PEX11B facilitates peroxisomal proliferation and interacts with PEX19

Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane

The enzyme plays an essential role in the carbohydrate metabolism

a class of myosins which are involved in the targeted transport of organelles

and typically associated with a poor prognosis

Raf-1 Polyclonal Antibody, 20ul[BT-AP13535] Immunoassays Peroxisomal biogenesis factor 11 betaThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.