Raf-1 Polyclonal Antibody, 20ul[BT-AP13531] Antibody Humanization |cofactor:Binds 3 calcium ions per

|cofactor:Binds 3 calcium ions per subunit

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

Mutations in this gene are associated with cardiomyopathy dilated type 1Z

It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation

PVRL3 plays a role in ocular development involving the ciliary body

Raf-1 Polyclonal Antibody, 20ul[BT-AP13531] Antibody Humanization |cofactor:Binds 3 calcium ions perThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.