Skp2 p45 Polyclonal Antibody, 100ul Glassware Sets Pyruvate dehydrogenase (PDH) is a

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals

Belongs to the Mediator complex subunit 28 family

Myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein

It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters

and nucleosome remodeling

Skp2 p45 Polyclonal Antibody, 100ul Glassware Sets Pyruvate dehydrogenase (PDH) is aSKP2 encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: fbws containing WD 40 domains, Fbls containing leucine rich repeats, and Fbxs containing either