EP400 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes These proteins are critical effectors

These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling| and they serve as targets for the small GTP binding proteins Cdc42 and Rac

The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines

This gene product appears to form only homodimers

which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

EP400 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes These proteins are critical effectors