Histone H2B Polyclonal Antibody, 20ul[BT-AP04032] Vacuum Filter and other cellular activities

and other cellular activities

The protein is localized to the centrosome and cilia and has sites for N-glycosylation

Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation

This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade

Histone H2B Polyclonal Antibody, 20ul[BT-AP04032] Vacuum Filter and other cellular activitiesHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.