Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions 2001 [PubMed 11242035])

2001 [PubMed 11242035])

Mutations in this gene result in primary ciliary dyskinesia-24

This gene may influence triglyceride levels| and may be involved Type 2 diabetes| as well as several types of cancer

but another polymorphism has been associated with increased plasma cholesterol levels

antibacterial response

Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions 2001 [PubMed 11242035])Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N terminus growth factors, extracellular matrix proteases modulating their activity.