Dkk-3 Monoclonal Antibody, 50ul Peripheral Blood Separation Tube The protein encoded by VPS72

The protein encoded by VPS72 (vacuolar protein sorting 72 homolog) is a shared subunit of two multi-component complexes

TTK (TTK protein kinase) encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine

Nup93 is composed of a coiled-coil domain at its N-terminus and a C-terminal helical domain

the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes

in de novo pyrimidine biosynthesis

Dkk-3 Monoclonal Antibody, 50ul Peripheral Blood Separation Tube The protein encoded by VPS72This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.