XRCC3 Polyclonal Antibody, 100ul[BT-AP09626] Dry Bath VCP and NPLOC4 binds ubiquitinated

VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm

Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons

The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization

Among its related pathways are Mineral absorption and Metal ion SLC transporters

A chromosomal translocation and gene fusion between this gene and zinc finger| MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient

XRCC3 Polyclonal Antibody, 100ul[BT-AP09626] Dry Bath VCP and NPLOC4 binds ubiquitinatedXRCC3 encodes a member of the RecA Rad51 related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair deficient mutant that exhibits hypersensitivity to a number of different DNA damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying