PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath LGR6 encodes a member of

LGR6 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily

through the regulation of MYPT1 and thus MLC2 phosphorylation

This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

LYL1 represents a basic helix-loop-helix transcription factor

PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath LGR6 encodes a member ofThis gene encodes a protein that may play a role in pre mRNA splicing. Chromosomal translocations (X; 1)(p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.