Neu Polyclonal Antibody, 100ul[BT-AP05905] Human Genome Knockout Libraries The protein encoded by this

The protein encoded by this gene may be involved in both peripheral and central nervous system development

This gene encodes a protein that is required for Notch pathway signaling| and for the activity and accumulation of gamma-secretase

hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19

Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19

Contains 20 C2H2-type zinc fingers

Neu Polyclonal Antibody, 100ul[BT-AP05905] Human Genome Knockout Libraries The protein encoded by thisERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Erb b2 receptor tyrosine kinase 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving