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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis This gene is expressed exclusively

SKU: 17544657673

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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis This gene is expressed exclusivelyThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

This gene is expressed exclusively in the brain

ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells

This protein is expressed by antigen-presenting cells| and it is the ligand for two proteins at the cell surface of T cells| CD28 antigen and cytotoxic T-lymphocyte-associated protein 4

Multiple transcript variants encoding at least two different isoforms have been described for this gene

Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis This gene is expressed exclusivelyThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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