IGF-IR Polyclonal Antibody, 100ul[BT-AP04397] Reagent Reservoirs forms laminin-5

forms laminin-5

thereby affecting various biological functions

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bronchial and small airway lung epithelial cells (at protein level)

Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity

IGF-IR Polyclonal Antibody, 100ul[BT-AP04397] Reagent Reservoirs forms laminin-5IGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms