SYT4 Polyclonal Antibody, 20ul Polyclonal Antibodies Mutations affecting this gene are

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

In fact| F-box proteins are one of the four subunits of ubiquitin protein ligases| called SCFs

Expressed specifically in the hippocampus and Purkinje cells of the brain

this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking

which subsequently combine as a tetramer to produce haptoglobin

SYT4 Polyclonal Antibody, 20ul Polyclonal Antibodies Mutations affecting this gene arecofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,May be involved in Ca(2+) dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,Belongs to the synaptotagmin family.,Contains 2 C2 domains.,tissue specificity: Expressed in brain. Within brain, expression is highest in hippocampus, with