ZN605 Rabbit Polyclonal Antibody, 100ul Enzymes & Activity Assays An important paralog of this

An important paralog of this gene is USP54

The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors

Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm

ThAKAP8 encodes a nuclear A-kinase anchor protein (A-kinase anchoring protein 8) that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin

It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases

ZN605 Rabbit Polyclonal Antibody, 100ul Enzymes & Activity Assays An important paralog of this