RNF4 Rabbit Polyclonal Antibody, 20ul Tubes |tissue specificity:Ubiquitous| with higher levels

|tissue specificity:Ubiquitous| with higher levels in heart| pancreas and testis| and lower levels in kidney and brain

When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner

PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1

CDC2 and RAC1

Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)

RNF4 Rabbit Polyclonal Antibody, 20ul Tubes |tissue specificity:Ubiquitous| with higher levelsThe protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with and inhibit the activity of TRPS1 a transcription suppressor of GATA mediated transcription. Transcription repressor ZNF278 PATZ is found to interact with this protein and thus reduce the enhancement of androgen receptor dependent transcription mediated by this protein. Studies of the mouse and rat