MIB2 Polyclonal Antibody, 100ul Modification Enzymes CAP-Gly domain containing linker protein

CAP-Gly domain containing linker protein 2 encoded by CLIP2 belongs to the family of cytoplasmic linker proteins

The product of NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex

This gene belongs to the guanine-binding protein (GBP) family

Participates in Wnt signaling (By similarity)

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

MIB2 Polyclonal Antibody, 100ul Modification Enzymes CAP-Gly domain containing linker proteinE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result