PLC gamma2(Phospho Tyr1217) Polyclonal Antibody, 20ul Funnels Mutations in this gene result

Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease

Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP)

Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease

subunit:Interacts with FLII

This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells

PLC gamma2(Phospho Tyr1217) Polyclonal Antibody, 20ul Funnels Mutations in this gene resultThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in