Factor I Polyclonal Antibody, 20ul Centrifuges RAPGEF1 encodes a human guanine

RAPGEF1 encodes a human guanine nucleotide exchange factor

The encoded protein is a strong inducer of lymphocyte apoptosis

1 µl to 10 ml

The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation

Jervell and Lange-Nielsen syndrome

Factor I Polyclonal Antibody, 20ul Centrifuges RAPGEF1 encodes a human guanineCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an