TFG Rabbit Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene have

Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers

AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites

Gene Ontology (GO) annotations related to this gene include calcium channel activity

The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility

a peptide encoded by the metastasis suppressor gene KISS1

TFG Rabbit Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene haveThere are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma and may play a role in the NF kappaB pathway. Multiple transcript variants have been found for this gene.