SMCE1 Polyclonal Antibody, 50ul Culture Plate Inserts This protein localizes to the

This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein

which is a member of the APP (amyloid precursor protein) family including APP

Defects in this gene are the cause of LIG4 syndrome

This fusion protein has also been associated with disruption of the cell cycle

This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains

SMCE1 Polyclonal Antibody, 50ul Culture Plate Inserts This protein localizes to theThe protein encoded by this gene is part of the large ATP dependent chromatin remodeling complex SWI SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI SNF complex, can bind to 4 way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA binding HMG domain, but disruption of this domain