Histone H3 Monoclonal Antibody, 20ul Monoclonal Antibody Preparation and these and other mutations

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

The lemur tyrosine kinase 2 encoded by LMTK2 belongs to the protein kinase superfamily and the protein tyrosine kinase family

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection

The gene product belongs to the TF2B family

Histone H3 Monoclonal Antibody, 20ul Monoclonal Antibody Preparation and these and other mutationsHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin