p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases Mutations in this gene result

Mutations in this gene result in one form of autosomal dominant hearing impairment

The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor

This protein is thought to be involved in intracellular signal transduction mechanisms

Detected at very low levels in brain

Defects in this gene are a cause of acid-labile subunit deficiency

p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases Mutations in this gene resultThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from