PARP-1 Polyclonal Antibody, 50ul[BT-AP12793] Electrophoresis & Labeling 2001 [PubMed 11689425])

2001 [PubMed 11689425])

It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

this protein can negatively regulate the cell survival serine-threonine kinase AKT1

The protein encoded by MAP4 is a major non-neuronal microtubule-associated protein

The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum

PARP-1 Polyclonal Antibody, 50ul[BT-AP12793] Electrophoresis & Labeling 2001 [PubMed 11689425])This gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be