NGAL Rabbit Polyclonal Antibody, 20ul[BT-AP11526] Cell Culture Plates Mutations in the gene are

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified

Additional splice variants have been described but sequences for the complete transcripts have not been determined

A related pseudogene has been identified on chromosome 6

This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes

NGAL Rabbit Polyclonal Antibody, 20ul[BT-AP11526] Cell Culture Plates Mutations in the gene areThis gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron containing siderophores. The presence of this protein in blood and urine is an early biomarker of